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Home » Gallery » PhD Theses » Thesis Elise Hovingh (2018)

Thesis Elise Hovingh (2018)

  • General introduction.
  • Emerging Bordetella pertussis strains induce enhanced signaling of human Pattern Recognition Receptors TLR2, NOD2 and secretion of IL-10 by Dendritic Cells.
  • Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor.
  • Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 of Bordetella pertussis results in C2 and C4 consumption away from the bacterial surface.
  • Virulence associated gene 8 enhances contact system activity by inhibiting the regulatory function of C1 inhibitor.
  • Opsonophagocytosis of a recently circulating Bordetella pertussis strain: in the search for correlates of protection.
  • Title: Unraveling the interactions between Bordetella pertusissis and the innate immune system
  • Author: Elise Hovingh
  • Year: 3 mei 2018

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Contact

Medical Microbiology

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Y.Hagenaar-2@umcutrecht.nl

Themes

  • Synthetic microbiology
  • Bacteria & Complement
  • Bacterial Glycobiology
  • Immune Evasion

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