General view of  inflammation
General view of inflammation


Evasion molecules that intervene with the initial phase of neutrophil extravasation from the bloodstream into tissue.

Inflammatory triggers initiate the slow rolling and subsequent attachment of neutrophils to the endothelial cells.

Subsequently the cells cross the endothelial cell barier and migrate along a gradient of chemo-attractants towards the site of infection.

Evasion molecules that intervene with complement activation on the Staphylococcus aureus surface.

Complement is activated via 3 routes leading to opsonization of the bacteria that are subsequently recoginized by phagocytes.