AefbExtracellular Complement binding protein (Ecb)

Ecb was identified by Ilse Jongerius in 2007. Ecb is homologues to the C-terminal part of Efb that binds complement C3. The complement inhibition is due to blocking C3b-containing convertases: the alternative pathway C3 convertase and the C5 convertases.





1) Staphylococcal complement evasion by various convertase-blocking molecules.

2) Convertase inhibitory properties of Staphylococcal extracellular complement-binding protein.

  • Accession number: SA1000
  • MW: 9.6 kDa
  • # Amino Acids: 80
  • PBD ID: not yet
  • Structure: